Overexpression of hMSH2 and hMLH1 protein in certain gastric cancers and their surrounding mucosae
نویسندگان
چکیده
منابع مشابه
Apoptosis induced by overexpression of hMSH2 or hMLH1.
Mutations of the mismatch repair genes hMSH2 and hMLH1 have been found in a high proportion of individuals with hereditary nonpolyposis colon cancer (HNPCC), establishing the link between mismatch repair and cancer. Tumor cell lines that are deficient in mismatch repair develop a mutator phenotype that appears to drive the accumulation of mutations required for tumor development. However, mutat...
متن کاملDefective hMSH2/hMLH1 protein expression is seen infrequently in ulcerative colitis associated colorectal cancers.
BACKGROUND Ulcerative colitis is associated with an increased risk of colorectal cancer above that of the normal population. The relative risk correlates with the extent and duration of the disease but the genetic basis of ulcerative colitis associated cancer risk is not known. AIMS To assess the prevalence of microsatellite instability and mismatch repair gene abnormalities in ulcerative col...
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epidemiological study of oral and pharyngeal cancers in kermanshah province from march 1993 to march 2006
چکیده ندارد.
15 صفحه اولthe relationship between learners critical thinking ability and their performance in the reading sections of the tofel and ielts test
the study reflected in this thesis aims at finding out relationships between critical thinking (ct), and the reading sections of tofel and ielts tests. the study tries to find any relationships between the ct ability of students and their performance on reading tests of tofel and academic ielts. however, no research has ever been conducted to investigate the relationship between ct and the read...
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ژورنال
عنوان ژورنال: Oncology Reports
سال: 2008
ISSN: 1021-335X,1791-2431
DOI: 10.3892/or.19.2.401